PEER-REVIEWED PUBLICATIONS

ORCID: 0000-0003-3834-7387

Research ID: L-6528-2016

Scopus ID: 57209707276

Google Scholar: https://scholar.google.co.kr/citations?user=jfzGZ5UAAAAJ&hl=en

 

* Corresponding Author, Equal Contribution

2024

86. Hui-Min Wang, Mengdi Geng, Jing Bai, Dezhong Zhou,* Weibo Hua, Sheng Liu,* Xueping Gao.* 'Comb-like Poly(β-amino ester)-intergrated PEO-based Self-healing Solid Electrolyte for Fast Ion Conduction in Lithium-sulfur Batteries'. Materials Horizons, 2024, DOI: 10.1039/D4MH01181C (IF=12.2)

85. Chenfei Wang, Wei He, Rui Guo, Chaolan Pan, Haiyang Yong, Tao Bo, Yitong Zhao, Zhili Li, Feifei Wang, Weiyi Xu, Dingjin Yao, Si Zhang,* Ming Li,* Dezhong Zhou.* 'Endoplasmic Reticulum-Targeting Highly Branched Poly(β-amino ester)s for Skin Gene Delivery'. ACS Materials Letters, 2024, 6, 5048-5057 (IF=9.6)

84. Chenfei Wang, Feifei Wang, Yuxing Zheng, Tao Bo, Yitong Zhao, Haiyang Yong, Zhili Li, Weiyi Xu, Qiang Zhao, Dezhong Zhou.* 'Enhancing Gene Transfection Efficiency of Star-Shaped Poly(β-amino ester)s via "Top-Down" Hydrolysis'. ACS Macro Letters, 2024, 13, 1218-1225 (IF=5.8)

83. Zhili Li, Dezhong Zhou.* 'Acrylate-Based PEG Hydrogels with Ultrafast Biodegradability for 3D Cell Culture'. Biomacromolecules, 2024, 25, 6195-6202 (IF=6.2)

82. Haiyang Yong,# Lixin Lin,# Zhili Li, Rui Guo, Chenfei Wang, Shuai Liu,* Dezhong Zhou.* 'Tailoring Highly Branched Poly(β-amino ester)s for Efficient and Organ-selective mRNA Delivery'. Nano Letters, 2024, 24, 9368-9376 (IF=10.7)

81. Zongnan Zhang, Xueli Lv, Xin Mu, Mengyao Zhao, Sichang Wang, Congyu Ke, Shujiang Ding,* Dezhong Zhou.Minyan Wang* Rong Zeng.* 'In-situ Noncovalent Interaction of Ammonium Ion Enabled C-H Bond Functionalization of Polyethylene Glycols'. Nature Communications, 2024, 15: 4445 (IF=16.6)

80. Zhili Li, Qijun Wo, Dongdong Huang, Dezhong Zhou.Lei Guo,* Yeqing Mao.* 'Improving Gene Transfection Efficiency of Highly Branched Poly(β-amino ester) Through the In-situ Conversion of Inactive Terminal Groups'. Chinese Chemical Letters, 2024, 35, 109737 (IF=9.1)

79. Zhili Li, Rui Guo, Zhiyong Zhang,* Haiyang Yong,* Lei Guo, Zhengju Chen, Dongdong Huang, Dezhong Zhou.* 'Enhancing Gene Transfection of Poly(β-amino ester)s through Modulation of Amphiphilicity and Chain Sequence'. Journal of Controlled Release, 2024, 368, 131-139 (IF=10.8)

78. Haiyang Yong, Zhili Li, Rui Guo, Dezhong Zhou.* 'Synthesis and Physiological Properties of Cyclized Poly(β-amino ester)s'. Chemical Journal of Chinese Universities, 2024, 45, 20230466

77. Ya-Nan Zhou, Haiyang Yong, Rui Guo, Kaixuan Wang, Zhili Li, Weibo Hua, Dezhong Zhou.* 'Self-reporting and Biodegradable Thermosetting Solid Polymer Electrolyte'. Angewandte Chemie International Edition, 2024, 63, e202319003 (IF=16.6)

76. Bin Ma, Jiahao Shi, Yuhe Zhang, Zhili Li, Haiyang Yong. Ya-Nan Zhou,* Shuai Liu,* Sigen A,* Dezhong Zhou.* 'Enzymatically Activatable Polymers for Disease Diagnosis and Treatment'. Advanced Materials, 2024, 2306358 (IF=29.4)

2023

75. Syed Saqib Ali Zaidi, Faria Fatima, Syed Aqib Ali Zaidi, Dezhong Zhou,* Wuquan Deng,* Shuai Liu.* 'Engineering siRNA Therapeutics: Challenges and Strategies'. Journal of Nanobiotechnology, 2023, 21: 381 (IF=10.2)

74. Yuhe Zhang, Jiahao Shi, Bin Ma, Ya-Nan Zhou, Haiyang Yong,* Jianzhong Li,* Xiangyi Kong,* Dezhong Zhou.* 'Functionalization of Polymers for Intracellular Protein Delivery'. Progress in Polymer Science, 2023, 146, 101751 (IF=27.1)

73. Jiahao Shi, Bin Ma, Yuhe Zhang, Haiyang Yong, Zhili Li, Sigen A,* Xiaobei Huang,* Dezhong Zhou.* 'Targeted Delivery of Anticancer Therapeutics with Polymers by Harnessing Tumor Microenvironment Acidity'. Chemistry of Materials, 2023, 35, 6573-6590 (IF=8.6)

72. Jiahao Shi, Yuhe Zhang, Bin Ma, Haiyang Yong,* Delu Che,* Chaolan Pan, Wei He, Dezhong Zhou,* Ming Li.* 'Enhancing the Gene Transfection of Poly(β-amino ester)/DNA Polyplexes by Modular Manipulation of Amphiphilicity'. ACS Applied Materials & Interfaces, 2023, 15, 36, 42130-42138 (IF=9.4)

71. Yuhe Zhang, Jiahao Shi, Bin Ma, Haiyang Yong, Zhili Li, Ya-Nan Zhou, Jianzhong Li,* Lirong Liang,* Dezhong Zhou.* 'Phosphocholine-Functionalized Zwitterionic Highly Branched Poly(β-amino ester)s for Cytoplasmic Protein Delivery'. ACS Macro Letters, 2023, 12, 626-631 (IF=5.8)

70. Zongnan Zhang, Xinyang Li, Dezhong Zhou, Shujiang Ding, Minyan Wang,* Rong Zeng.* 'Controllable C-H Alkylation of Polyethers Via Iron Photocatalysis'. Journal of the American Chemical Society, 2023, 145, 7612-7620 (IF=14.9)

69. Zhili Li,# Haiyang Yong,#,* Kaixuan Wang, Ya-Nan Zhou, Jing Lyu,* Lirong Liang,* Dezhong Zhou.* '(Controlled) Free Radical (Co)Polymerization of Multivinyl Monomers: Strategies, Topological Structures and Biomedical Applications'. Chemical Communications, 2023, 59, 4142-4157 (IF=4.9)

68. Ya-Nan Zhou, Zichun Xiao, Duzhao Han, Suning Wang, Jinniu Chen, Wei Tang,* Mingyu Yang, Le Shao, Chengyong Shu, Weibo Hua,* Dezhong Zhou,* Yuping Wu. 'Inhibition of the P3-O3 Phase Transition via Local Symmetry Tuning in P3-Type Layered Cathodes for Ultra-stable Sodium Storage'. Journal of Materials Chemistry A, 2023, 11, 2618-2626 (IF=11.9)

67. Delu Che,# Chenfei Wang,#,* Zhili Li,#  Kaixuan Wang,# Shuaiwei Sun, Xinyue Zhang, Yi Li,# Zhengju Chen, Lei Guo, Yajing Hou, Dezhong Zhou,* Songmei Geng.* 'Efficient Gene Transfection of Suspension Cells by Highly Branched Poly(β-amino ester)'. Chinese Chemical Letters, 2023, 34, 108066 (IF=9.1)

66. Chenfei Wang, Litao Sun, Qiuxia Li, Zhili Li, Chengyuan Xu, Xinyue Zhang, Jianjun Shi,* Hao Zhou,* Wenxin Wang, Dezhong Zhou.* 'Highly Branched Poly(β-amino ester)s with Narrow Molecular Weight Distribution: Fractionation and Gene Transfection Activity'. Chinese Chemical Letters, 2023, 34, 107627 (IF=9.1)

65. Ya-Nan Zhou, Weibo Hua, Dezhong Zhou.* 'Understanding the Na+ Transport Kinetics and Phase Transition Mechanism of O3-NaNi0.4Fe0.2Mn0.4O2 Cathode Materials'. Energy Storage Science and Technology, 2023, 12, 1011-1017

2022

64. Haiyang Yong,# Zhili Li,# Xiaobei Huang,#  Kaixuan Wang, Ya-Nan Zhou, Qiuxia Li, Jianjun Shi,* Ming Liu, Dezhong Zhou.* 'Superhydrophobic Materials: Versatility and Translational Applications'. Advanced Materials Interfaces, 2022, 2200435 (IF=5.3)

63. Qiuxia Li,# Litao Sun,# Xiaobei Huang,# Shuai Liu,* Haiyang Yong, Chenfei Wang, Jianzhong Li,* Dezhong Zhou.* ‘Genetic Engineering of Adipose-Derived Stem Cells Using Biodegradable and Lipid-Like Highly Branched Poly(β-amino ester)s’. ACS Macro Letters, 2022, 11, 636-642 (IF=5.8)

62. Ya-Nan Zhou, Zichun Xiao, Duzhao Han, Lianping Yang,Jiyong Zhang, Wei Tang,* Chengyong Shu, Chengxin Peng,* Dezhong Zhou.* ‘Approaching Practically Accessible and Environmentally Adaptive Sodium Metal Batteries with High Loading Cathodes through In Situ Interlock Interface’. Advanced Functional Materials, 2022, 2111314 (IF=19.0)

61. Chenfei Wang,# Xiaobei Huang,# Litao Sun, Qiuxia Li, Zhili Li, Haiyang Yong, Delu Che, Cong Yan, Songmei Geng,* Wenxin Wang, Dezhong Zhou.* ‘Cyclic Poly(β-amino ester)s with Enhanced Gene Transfection Activity Synthesized through Intra-molecular Cyclization’. Chemical Communications, 2022,  58, 2136-2139 (IF=4.9)

60. Jonathan O'Keeffe Ahern, Irene Lara-Saez, Dezhong Zhou, Rodolfo Murillas, Angeles Mencia, Marta Garcia, Dario Manzanares, Jennifer Lynch,Ruth Foley, Qian Xu, Sigen A, Fernando Larcher, Wang, W.* ‘Non-viral Delivery of CRISPR-Cas9 Complexes for Targeted Gene Editing via A Polymer Delivery System’. Gene Therapy, 2022, 29, 157-170 (IF=6.3)

2021

59. Ming Zeng, Qian Xu, Dezhong Zhou,* Sigen A, Fatma Alshehri, Irene Lara-Saez, Yue Zheng, Ming Li,* Wenxin Wang.* ‘Highly Branched Poly(β-amino ester)s for Gene Delivery in Hereditary Skin Diseases’. Advanced Drug Delivery Reviews, 2021,  176,  113842  (IF=16.1)

58. Sigen A, Qian Xu, Melissa Johnson, Jack Creagh-Flynn, Manon Venet, Dezhong Zhou, Irene Lara-Saez, Hongyun Tai, Wenxin Wang.* ‘An Injectable Multi-responsive Hydrogel as Self-healable and On-mand Dissolution Tissue Adhesive’. Applied Materials Today, 2021, 22, 100967  (IF=10.041)

2020

57. Xiangwen Gao, Ya-Nan Zhou, Duzhao Han, Jiangqi Zhou, Dezhong Zhou, Wei Tang,* John B. Goodenough.* ‘Thermodynamic Understanding of Li-Dendrite Formation’. Joule, 2020, 4, 1-16  (IF=39.7)

56. Sigen A, Jing Lyu,Melissa Johnson, Jack Creagh-Flynn, Dezhong Zhou, Irene Lara-Saez, Qian Xu, Hongyun Tai, Wenxin Wang.* ‘Instant Gelation System as Self-Healable and Printable 3D Cell Culture Bioink Based on Dynamic Covalent Chemistry’. ACS Applied Materials & Interfaces, 2020, 12, 38918-38924  (IF=9.4)

55. Xiaolin Li, Sigen A, Qian Xu, Fatma Alshehri, Ming Zeng, Dezhong Zhou, Jun Li, Guangqian Zhou, Wenxin Wang.* ‘Cartilage Derived Progenitor Cell-Laden Injectable Hydrogel - An Approach for Cartilage Tissue Regeneration’. ACS Applied Bio Materials, 2020, 3, 4756-4765  (IF=4.7)

54. Yongsheng Gao,# Dezhong Zhou,#,* Jing Lyu,# Sigen A, Qian Xu, Newland Newland, Krzysztof Matyjaszewski, Hongyun Tai, Wenxin Wang.* ‘Complex Polymer Architectures Through Free-radical Polymerization of Multivinyl Monomers’. Nature Reviews Chemistry, 2020, 4, 194-212  (IF=36.3)

53. Yao Wang,# Chenfei Wang,# Ming Li, Dezhong Zhou,* Wei Huang, Wenxin Wang.* ‘Effects of Branching Strategy on the Gene Transfection of Highly Branched Poly(β-amino ester)s’. Chinese Journal of Polymer Science, 2020, 38, 830-839  (IF=4.2)

2019

52. Dezhong Zhou, Ming Zeng, Yongsheng Gao, Sigen A, Jing Lyu, Wenxin Wang. ‘Advanced Polymers for Gene Delivery’. Chapter 10 in the book Nucleic Acid Nanotheranostics: Biomedical Applications (ISBN: 9780128144701, Edited by Marco Filice & Jesus Ruiz-Cabello), Elsevier Publisher, 2019, 311-364

51. Shuai Liu,# Yongsheng Gao,# Dezhong Zhou,#,* Ming Zeng, Fatma Alshehri, Ben Newland, Jing Lyu, Jonathan O’Keeffe-Ahern, Udo Greiser, Tianying Guo,* Fengzhi Zhang, Wenxin Wang.* ‘Highly Branched Poly(ß-amino ester) Delivery of Minicircle DNA for Transfection of Neurodegenerative Related Diseases’. Nature Communications, 2019, 10: 3307  (IF=16.6)

50. Qian Xu, Sigen A, Manon Venet, Yongsheng Gao, Dezhong Zhou,* Wei Wang, Ming Zeng, Chiara Rotella, Xiaolin Li, Xi Wang, Jing Lyu, Brian J. Rodriguez, Wenxin Wang.* ‘Bacteria-Resistant Single Chain Cyclized/Knotted Polymer Coatings’ Angewandte Chemie, 2019, 131, 10726-10730 (IF=16.6)

49. Ming Zeng, Dezhong Zhou,* Fatama Alshehri, Irene Lara-Saez, Yuanning Lyu, Jack Creagh-Flynn, Qian Xu, Jing Zhang, Wenxin Wang.* ‘Manipulation of Transgene Expression in Fibroblast Cells by A Multifunctional Linear-Branched Hybrid Poly(β-Amino Ester) Synthesized through an Oligomer Combination Approach' Nano Letters, 2019, 19, 381-391 (IF=10.7)

48.  Ming Zeng, Fatma Alshehri, Dezhong Zhou,*  Irene Lara-Saez, Xi Wang, Xiaolin Li, Sigen A, Qian Xu, Jing Zhang, Wenxin Wang.* ‘Efficient and Robust Highly Branched Poly(β-amino ester)/Minicircle COL7A1 Polymeric Nanoparticles for Gene delivery to Recessive Dystrophic Epidermolysis Bullosa Keratinocytes’. ACS Applied Materials & Interfaces, 2019, 11 (34), 30661-30672 (IF=9.4)

 47. Haiyang Yong, Yongpeng Miao, Sigen A,* Dong Quan, Alojz Ivankovic, Krutika Singh, Jiang Zhang, Zhou, D., Wenxin Wang.* ‘Branched Polystyrenes from Suspension “Strathclyde” Polymerization Using A vulcanization Accelerator as a Chain Transfer Agent’. Polymer Chemistry, 2019, 10, 885-890 (IF=4.6)

 

2018

46.  Zhao Meng, Dezhong Zhou,* Yongsheng Gao, Ming Zeng, Wenxin Wang.* ‘miRNA Delivery for Skin Wound Healing’. Advanced Drug Delivery Reviews, 2018, 129, 308-318 (IF=16.1)

45. Jing Zhang,# Haiyang Yong,# Sigen A, Qian Xu, Yongpeng Miao, Jing Lyu, Yongsheng Gao, Ming Zeng, Dezhong Zhou,* Ziyi Yu, Hongyun Tai, Wenxin Wang.* ‘Structural Design of Robust and Biocompatible Photonic Hydrogels from an In Situ Cross-Linked Hyperbranched Polymer System’. Chemistry of Materials, 2018, 30, 6091-6098 (IF=8.6)

44. Sigen A,# Qian Xu,# Peter McMichael, Yongsheng Gao, Xiaolin Li, Xi Wang, Udo Greiser, Dezhong Zhou,* Wenxin Wang.* ‘A Facile One-pot Synthesis of Acrylated Hyaluronic Acid’. Chemical Communications, 2018, 54, 1081-1084 (IF=4.9)

43. Jonathan O’Keeffe Ahern,# Sigen A,# Dezhong Zhou,* Yongsheng Gao, Jing Lyu, Zhao Meng, Lara Cutlar, Lara Pierucci, Wenxin Wang.* ‘Brush-like cationic polymers with low charge density for gene delivery’, Biomacromolecules, 2018, 19, 1410-1415 (IF=6.2)

42. Xiaobei Huang, Dezhong Zhou,* Sigen A, Yongsheng Gao, Xi Wang, Xiaolin Li, Qian Xu, Udo Greiser, Guangfu Yin,* Wenxin Wang. ‘Star Polymers from Single-Chain Cyclized/Knotted Nanoparticles as a Core’, Macromolecular Chemistry  and Physics, 2018, 219, 1700473 (IF=2.5)

41.  Qian Xu, Linru Guo, Sigen A, Yongsheng Gao, Dezhong Zhou, Udo Greiser, Jack Creagh-Flynn, Hong Zhang, Yixiao Dong, Lara Cutlar, Fagang Wang, Wenguang Liu, Wei Wang,* Wenxin Wang.* ‘Injectable Hyperbranched Poly(β-amino ester) Hydrogels with On-Demand Degradation Profile to Match Wound Healing Process’. Chemical Science, 2018, 9, 2179-2187 (IF=8.4)

40. Qian Xu, Sigen A,* Peter McMichael, Jack Creagh-Flynn, Dezhong Zhou, Yongsheng Gao, Xiaolin Li, Xi Wang, Wenxin Wang.* ‘Double-Cross-Linked Hydrogel Strengthened by UV Irradiation from a Hyperbranched PEG-Based Trifunctional Polymer’. ACS Macro Letters, 2018, 7, 509-513 (IF=5.8)

39. Qian Xu, Manon Venet, Wei Wang, Jack Creagh-Flynn, Xi Wang, Xiaolin Li, Yongsheng Gao, Dezhong Zhou, Ming Zeng, Irene Lara-Saez, Sigen A,* Hongyun Tai, Wenxin Wang.* ‘Versatile Hyperbranched Poly(β-hydrazide ester) Macromers as Injectable Antioxidative Hydrogels’. ACS Applied Materials & Interfaces, 2018, 10, 39494-39504(IF=9.5)

38.  Qian Xu, Sigen A, Yongsheng Gao, Linru Guo, Jack Creagh-Flynn, Dezhong Zhou, Udo Greiser, Yixiao Dong, Fagang Wang, Hongyun Tai, Wenguang Liu, Wei Wang,* Wenxin Wang.* ‘A Hybrid Injectable Hydrogel from Hyperbranched PEG Macromer as a Stem Cell Delivery and Retention Platform for Diabetic Wound Healing’. Acta Biomaterialia, 2018, 75, 63-74 (IF=9.7)

 

2017

37.  Shuai Liu,# Dezhong Zhou,# Jixiang Yang, Hao Zhou, Jiatong Chen, Tianying Guo.* ‘Bioreducible Zinc(II) Coordinative PEI with Low Molecular Weight for Robust Gene Delivery of Primary and Stem Cells’. Journal of the American Chemical Society, 2017, 139, 5102-5109 (IF=15.0)

36. Yongsheng Gao,# Ben Newland,# Dezhong Zhou,# Krzysztof Matyjaszewski, Wenxin Wang.* ‘Controlled Polymerization of Multivinyl Monomers: Toward Single Chain Cyclized/Knotted Polymer Architecture’. Angewandte Chemie International Edition, 2017, 56, 450-460 (IF=16.6)

35.  Xiaobei Huang, Dezhong Zhou* Ming Zeng, Fatma Alshehri, Xiaolin Li, Jonathan O’Keeffe Ahern, Yongsheng Gao, Luca Pierucci, Udo Greiser, Guangfu Yin,* Wenxin Wang.* ‘Star Poly(β-amino esters) Obtained from the Combination of Linear Poly(β-amino esters) and Polyethylenimine’. ACS Macro Letters, 2017, 6, 575-579 (IF=5.8)

34. Dezhong Zhou,# Luca Pierucci,# Yongsheng Gao,# Jonathan O’Keeffe Ahern, Xiaobei Huang, Sigen A, Wenxin Wang.* ‘Thermo- and pH-Responsive, Coacervate-forming Hyperbranched Poly(β-amino ester)s for Selective Cell Binding’. ACS Applied Materials & Interfaces, 2017, 9, 5793-5802 (IF=9.5)

33. Zhao Meng, Jonathan O’Keeffe-Ahern, Jing Lyu, Luca Pierucci, Dezhong Zhou,* Wenxin Wang.* ‘A New Developing Class of Gene Delivery: Messenger RNA-based Therapeutics’, Biomaterials Science, 2017, 5, 2381-2392 (IF=6.6)

32.  Shuai Liu, Yongsheng Gao, Sigen A, Dezhong Zhou,* Udo Greiser, Tianying Guo, Rui Guo, Wenxin Wang.* ‘Biodegradable Highly Branched Poly(β-amino ester)s for Targeted Cancer Cell Gene Transfection’. ACS Biomaterials Science & Engineering, 2017, 3, 1283-1286 (IF=5.8)

31.  Shuai Liu,# Zhibin Sun,# Dezhong Zhou,* Tianying Guo.* ‘Alkylated Branched Poly(β-amino esters) Demonstrate Strong DNA Encapsulation, High Nanoparticle Stability and Robust Gene Transfection Efficacy’, Journal of Materials Chemistry B, 2017, 5, 5307-5310 (IF=7.0)

30.  Ming Zeng, Dezhong Zhou,* Singwei Ng, Jonathan O’Keeffe, Fatma Alshehri, Yongsheng Gao, Luca Pierucci, Udo Greiser, Wenxin Wang.* ‘Highly Branched poly(5-amino-1-pentanol-co-1,4-butanediol diacrylate) for High Performance Gene Transfection’. Polymers, 2017, 161, 1-11 (IF=5.0)

29.  Sigen A, Qian Xu, Dezhong Zhou, Yongsheng Gao, Jeddah Marie Vasquez, Udo Greiser, Wenxin Wang, Wenguang Liu, Wenxin Wang.* ‘Hyperbranched PEG-based Multi-NHS Polymer and Bioconjugation with BSA’. Polymer Chemistry, 2017, 8, 1283-1287 (IF=4.6)

28. Sirong Li, Linru Guo, Yongsheng Gao,* Dezhong Zhou, Wenxin Wang.* ‘Viscoelastic Study of Single Chain Cyclized Polymeric Nanoparticles and Linear Polymers Blends’. Acta Polymerica Sinica, 2017, 2, 386-392 (IF=1.9)

 

2016

27.  Dezhong Zhou,# Lara Cutlar,# Yongsheng Gao,# Wei Wang, Jonathan O’Keeffe-Ahern, Sean McMahon, Branca Duarte, Fernando Larcher, Brian J. Rodriguez, Udo Greiser, Wenxin Wang.* ‘The Transition from Linear to Highly Branched Poly(β-amino ester)s: Branching Matters for Gene Delivery’. Science Advances, 2016, 2, e1600102 (IF=13.6)

26. Dezhong Zhou,# Yongsheng Gao,# Sigen A, Qian Xu, Zhao Meng, Udo Greiser, Wenxin Wang.* ‘Anticancer Drug Disulfiram (DS) for In-situ RAFT Polymerization: Controlled Polymerization, Multi-facet Self-assembly and Efficient Drug Delivery’. ACS Macro Letters, 2016, 5, 1266-1272 (IF=5.8)

25.  Dezhong Zhou, Yongsheng Gao,# Jonathan O’Keeffe-Ahern, Sigen A, Qian Xu, Xiaobei Huang, Udo Greiser, Wenxin Wang.* ‘Development of Branched Poly(5-amino-1-pentanol-co-1,4-butanediol diacrylate) with High Gene Transfection Potency across Diverse Cell Types’. ACS Applied Materials & Interfaces, 2016, 34218-34226 (IF=9.5, Q1)

24. Dezhong Zhou, Ahmed Aied,# Lara Cutlar,# Yongsheng Gao,# Olga Igoucheva, Ben Newland, Vitali Alexeeve, Udo Greiser, Jouni Uitto, Wenxin Wang.* ‘Highly Branched Poly(β-amino ester)s for Targeted Skin Gene Therapy’. Journal of Controlled Release, 2016, 244, 336-346 (IF=10.8)

23.  Yongsheng Gao,# Jian-Yuan Huang,# Jonathan O’Keeffe-Ahern, Lara Cutlar, Dezhong Zhou,* Fei-Huo Lin, Wenxin Wang.* ‘Highly Branched Poly(β-amino esters) for Non-Viral Gene Delivery: High Transfection Efficiency and Low Toxicity Achieved by Increasing Molecular Weight’. Biomacromolecules, 2016, 3640-3647 (IF=6.2)

22. Lara Cutlar,# Ahmed Aied,# Yongsheng Gao,# Udo Greiser, Eva Maria Murauer, Dezhong Zhou,* Wenxin Wang.* ‘A Knot Polymer Mediated Non-viral Gene Transfection for Skin Cells'. Biomaterials Science, 2016, 4, 92-95 (IF=6.6)

21. Shuai Liu, Jixiang Yang, Hongqi Ren, Jonathan O’Keeffe-Ahern, Dezhong Zhou,* Hao Zhou, Jiatong Chen, Tianying Guo.* ‘Multifunctional Oligomer Incorporation: A Potent Strategy to Enhance the Transfection Activity of Poly(l-lysine)’. Biomaterials Science, 2016, 4, 522-532 (IF=6.6)

20.  Zhibin Sun,* Dezhong Zhou,* ‘PLL/PAE/DNA Ternary Complexes with Enhanced Endosomal Escape Ability for Efficient and Safe Gene Transfection’. New Journal of Chemistry, 2016, 40, 9806-9812 (IF=3.3)

19. Lara Cutlar,# Dezhong Zhou,# Xuejun Hu, Branca Duarte, Udo Greiser, Fernando Larcher, Wenxin Wang.* 'A Non-Viral Gene Therapy for Treatment of Recessive Dystrophic Epidermolysis Bullosa'. Experimental Dermatology, 2016, 25, 818-820 (IF=4.1)

18.  Yongsheng Gao,# Verenal I. Bohmer,# Dezhong Zhou, Tianyu Zhao, Wenxin Wang,* Jos M.J. Paulusse.* ‘Main-Chain Degradable Single-Chain Cyclized Polymers as Gene Delivery Vectors’. Journal of Controlled Release, 2016, 244, 375-383 (IF=10.8)

17. Ben Newland,* Paul Wolff, Dezhong Zhou, Wei Wang, Hong Zhang, Anne Rosser, Wenxin Wang, Castern Werner.* 'Synthesis of ROS Scavenging Microspheres from a Dopamine Containing Poly(β-amino ester) for Applications for Neurodegenerative Disorders'. Biomaterials Science, 2016, 4, 400-404 (IF=6.6)

 

2015

16. Jian-Yuan Huang, Yongsheng Gao, Lara Cutlar, Jonathan O’Keeffe-Ahern, Tianyu Zhao, Fei-Huo Lin, Dezhong Zhou,* Sean McMahon, Udo Greiser, Wei Wang, Wenxin Wang.* 'Tailoring Highly Branched Poly (β-amino ester)s: A Synthetic Platform for Epidermal Gene Therapy', Chemical Communications, 2015, 51, 8473-8476 (IF=4.9)

15. Lara Cutlar,# Dezhong Zhou,#,* Yongsheng Gao, Tianyu Zhao, Udo Greiser, Wei Wang, Wenxin Wang.* Highly Branched Poly(β-amino esters): Synthesis and Application in Gene Delivery'. Biomacromolecules, 2015, 16(9), 2609-2617 (IF=6.2)

14. Yongsheng Gao, Dezhong Zhou, Tianyu Zhao, Xuan Wei, Sean McMahon, Jonathan O’Keeffe-Ahern, Wei Wang, Udo Greiser, Brian J. Rodriguez, Wenxin Wang.* ‘Intramolecular Cyclization Dominating Homopolymerization of Multivinyl Monomers toward Single Chain Cyclized/knotted Polymeric Nanoparticles'. Macromolecules, 2015, 48, 6882-6889 (IF=5.5)

13. Yongsheng Gao, Tianyu Zhao, Dezhong Zhou, Udo Greiser, Wenxin Wang.* ‘Insights into Relevant Mechanistic Aspects about the Induction Period of Cu0/Me6TREN Mediated Reversible - Deactivation Radical Polymerization'. Chemical Communications, 2015. 51, 14435-14438 (IF=4.9)

12. Yixiao Dong,* Yue Qin, Marie Dubaa, John Killion, Yongsheng Gao, Tianyu Zhao, Dezhong Zhou, Dominik Duscher, Luke Geever, L., Geoffery Gurtner, Wenxin Wang.* ‘A Rapid Crosslinking Injectable Hydrogel for Stem Cell Delivery, from Multifunctional Hyperbranched Polymers via RAFT Homopolymerization of PEGDA'. Polymer Chemistry, 2015. 6, 6182-6192 (IF=4.6)

11. Tianyu Zhao, Hong Zhang, H., Dezhong Zhou, Yongsheng Gao, Yixiao Dong, Udo Greiser, Hongyun Tai, Wenxin Wang.* 'Water Soluble Hyperbranched Polymers from Controlled Radical Homopolymerization of PEG Diacrylate’ RSC Advances, 2015, 5, 33823–33830 (IF=3.9)

 

2014

10.  Tianyu Zhao, Hong Zhang, Ben Newland, Ahmed Aied, Dezhong Zhou, Wenxin Wang.* ‘Significance of Branching for Transfection: Synthesis of Highly Branched Degradable Functional Poly(Dimethylaminoethyl Methacrylate) by Vinyl Oligomer Combination’. Angewandte Chemie International Edition, 2014, 53, 6095-6100 (IF=16.6)

2013

9.  Shuai Liu, Dezhong Zhou, Tianying Guo.* ‘Construction of A Novel Macroporous Imprinted Biosensor Based on Quartz Crystal Microbalance for Ribonuclease A Detection'. Biosensors & Bioelectronics, 2013, 42, 80-86 (IF=12.6)

8.  Yuling Hu, Dezhong Zhou, Congxin Li, Hao Zhou, Jiatong Chen, Zhengpu Zhang, Tianying Guo.* ‘Gene Delivery of PEI Incorporating with Functional Block Copolymer via Non-covalent Assembly Strategy’. Acta Biomaterialia, 2013, 5003, 5012 (IF=9.7)

 

2012

7.     Dezhong Zhou, Congxin Li, Yuling Hu, Hao Zhou, Jiatong Chen, Zhengpu Zhang, Tianying Guo.* ‘The Effects of a Multifunctional Oligomer and Its Incorporation Strategies on the Gene Delivery Efficiency of Poly(l-lysine)’. Chemical Communications, 2012, 48, 4594-4596 (IF=4.9)

6.   Dezhong Zhou, Congxin Li, Yuling Hu, Hao Zhou, Jiatong Chen, Zhengpu Zhang, Tianying Guo.* ‘PLL/pDNA/P(His-co-DMAEL) Ternary Complexes: Assembly, Stability and Gene Delivery’. Journal of Materials Chemistry, 2012, 22, 10743-10751 (IF=7.0)

5.  Dezhong Zhou, Congxin Li, Yuling Hu, Hao Zhou, Jiatong Chen, Zhengpu Zhang, Tianying Guo.* ‘Glycopolymer Modification on Physicochemical and Biological Properties of Poly(l-lysine) for Gene Delivery’. International Journal of Biological Macromolecules, 2012, 50, 965-973 (IF=8.1)

4.   Congxin Li, Dezhong Zhou, Yuling Hu, Hao Zhou, Shufang Wang, Jiatong Chen, Zhengpu Zhang, Tianying Guo.* ‘The Target Gene Carrying Validity to HepG2 Cells with the Brush-like Glutathione Modified Chitosan Compound’. Carbohydrate Polymers, 2012, 89, 46-53 (IF=11.2)

 

2011

3.   Dezhong Zhou, Tianying Guo,* Ying Yang, Zhengpu Zhang. ‘Surface Imprinted Macroporous Film for High Performance Protein Recoginition in Combination with Quartz Crystal Microbalance’. Sensors and Actuators B-Chemical, 2011, 153, 96-102 (IF=8.4)

2.  Congxin Li, Tianying Guo,* Dezhong Zhou, Yuling Hu, Hao Zhou, Shufang Wang, Jiatong Chen, Zhengpu Zhang. ‘A Novel Glutathione Modified Chitosan Conjugate for Efficient Gene Delivery’. Journal of Controlled Release, 2011, 154, 177-188 (IF=10.8)

1.  Huang Yang, Tianying Guo,* Dezhong Zhou. ‘Surface Hydrophilic Modification with Well-defined Glycopolymer for Protein Imprinting Matrix’. International Journal of Biological Macromolecules, 2011, 48, 432-438  (IF=8.1)

CONFERENCE ABSTRACTS

18.  ‘Hyperbranched Cationic Polymers as Non-viral Vectors Using Different Strategies for Potential Genetic Rare Diseases Treatment’. Lara-Sáez, I., O’Keeffe Ahern, J., Alshehri, F., Zeng, M., Murrillas, R., Larcher, F., Bonafont, J., Duarte, B., Zhou, D., and Wang, W., The 2019 TERMIS-EU Congress, Rhodes, Greece, May 2019

17.  Cartilage Derived Progenitor Cell-laden Injectable Hydrogel - A New Approach for Cartilage Regeneration’. Li, X, A, S., Dong, Y., Xu, Q., Zhou, D., Zhou, G., and Wang, W., The 2019 TERMIS-EU Congress, Rhodes, Greece, May 2019.

16.  ‘CRISPR/Cas9 Based COL7A1 Gene Editing in RDEB via Non-viral Polymer Delivery System’. O’Keeffe Ahern, J., Lara-Sáez, I., Murrillas, R., Larcher, F., Bonafont, J., Duarte, B., Zhou, D., and Wang, W., The 2019 TERMIS-EU Congress, Rhodes, Greece, May 2019.

15. ‘Fabrication of Hyperbranched PEG Polymers with Multiple Functional Groups: A Promising Class of Materials in Micro/Nano Manufacturing’. Lyu, J., Zhang, J., A, S., Xu, Q., Zhou, D., Tai, H., and Wang, W., The 6th International Polymer Replication on Nanoscale (PRN) Conference, Dublin, Ireland, May 2019.

14.  ‘Highly Branched Poly(β-amino ester)s as New Gene Delivery Vectors’. Zhou, D., Wang, W. The 7th China-Europe Symposium on Biomaterials In Regenerative Medicine (CESB 2019), Guangzhou, China, May 2019

13.   ‘Development of Highly Branched Poly(β-amino esters) as a New Generation of Gene Delivery Vectors’. Zhou, D., Wang, W. Macro Group UK YRM 2018, Dublin, Ireland, Jul. 2018

12.  ‘Highly Branched Poly(β-amino ester)s as New Gene Delivery Vectors’. Zhou, D. Wang, W. The 5th TERMIS World Congress, Kyoto, Japan, September 2018

11.  ‘A Simple, Efficient Non-viral Gene Therapy for Recessive Dystrophic Epidermolysis Bullosa’. Cutlar, L., Zhou, D., Hu, X., Duarte, B., Larcher, F. and Wang, W. Bioprocessing of Advanced Cellular Therapies Congress, London, UK, June 2016

10.  ‘Highly Branched Poly(β-amino ester)s as New Gene Delivery Vectors for the treatment of RDEB’. Zhou, D., Cutlar, L., Aied, A., Uitto, J., Larcher, F. and Wang, W. TERMIS-EU Conference, Uppsala, Sweden, June 2016

9.   ‘A Simple, Efficient Non-Viral Gene Therapy for Recessive Dystrophic Epidermolysis Bullosa’. Cutlar, L., Zhou, D., Hu, X., Duarte, B., Larcher, F. and Wang, W. Society for Investigative Dermatology 75th Annual Meeting, Scottsdale, Arizona, May 2016

8.   ‘Highly Branched Poly(β-amino ester)s as New Gene Delivery Vectors’. Cutlar, L., Zhou, D., Hu, X., Duarte, B., Larcher, F. and Wang, W. The 14th European Symposium on Controlled Drug Delivery, Amsterdam, Holland, April 2016

7.    ‘Skin Substitute with Adipose-Derived Stem Cells for Wound Healing, from an Injectable Hydrogel System’. Dong, Y., Khong, S., Rodrigues, M., Li, A.Y., Zhou, D., Gao, Y., Brett, E.A., Wang, W. and Gurtner, G.C. 2016 WHS Annual Meeting, Atlanta, Georgia, April 2016

6.   ‘Highly Branched Poly(β-amino ester)s as New Gene Delivery Vectors’. Zhou, D., Cutlar, L., Aied, A., Uitto, J., Larcher, F. and Wang, W. 4th TERMIS  World Congress, Boston, MA, U.S.A., September 2015

5.   ‘A Simple Efficient Non-viral Gene Therapy for Recessive Dystrophic Epidermolysis Bullosa’. Cutlar, L., Zhou, D., Hu, X., Duarte, B., Larcher, F. and Wang, W. DEBRA International, Atlanta, Georgia, May 2015

4.   ‘The Controlled/Living Radical Homopolymerization of Multivinyl Monomers: Toward Single Chain Cyclized Polymers’. Gao, Y., Zhao, T., Zhou D. and Wang, W. International  Conference  on  Advances  in  Functional  Materials, New York,  U.S.A., June 2015

3.     ‘Optimized DNA Constructs for Topical Recessive Dystrophic Epidermolysis Bullosa Gene Therapy’. Cutlar, L., Zhou, D., Hu, X. and Wang, W. UCD Conway Festival of Research and Innovation, Dublin, Ireland, September 2014

2.     ‘Design and Construction of a COL7A1 Minicircle For Non-viral Gene Therapy to Treat Recessive Dystrophic Epidermolysis Bullosa’, Cutlar, L., Zhou, D., Hu, X. and Wang, W. 3rd Minicircle& DNA Vector Conference, Bielefeld, Germany, May 2014

1.     ‘PEGMA-b-MAH Incorporated PEI Based Ternary Complexes with High Efficiency in Serum for Gene Delivery” Zhou, D., Hu, Y., Guo, T. 7th International Symposium on High-Tech Polymer Materials (HIPM-VII), Xi’an, China, June 2012

PATENTS

5.  Zhou, D. ‘Temperature-sensitive coacervation layer type hyperbranched polyethylene glycol, and preparation method and application thereof’, Patent No. ZL201911404380.4

4. Wang, W., Zhou, D. ‘Hyperbranched poly(β-amino ester) for gene therapy’, Patent No. PCT/EP2015/068153. This patent was licensed to Amryt Pharma PLC in March 2018: http://www.proactiveinvestors.co.uk/companies/stocktube/8885/amryt-pharma-signs-major-licensing-deal-for-gene-therapy-asset-8885.html

3.  Guo, T., Zhou, D., Li, C., Hu, Y. ‘Functional oligomer used for non-viral gene vector materials and application thereof’, Patent No. ZL201110440162.3

2. Guo, T., Li, C., Zhou, D., Hu, Y. ‘Glutathione-modified chitosan copolymer serving as non-Viral gene carrier material and preparation and application thereof’, Patent No. ZL201010601008.5

1. Wang, W., Wang, W., Zhou, D., Xu, Q., Zheng, Y., Yu, Z. ‘A well biocompatible injectable hydrogel and preparation method and application thereof’, Patent No. CN105176080B