承担项目

（1）2003.10～2005.10，“HIFU治疗瞬态损伤机制及监控成像方法研究”,校基金项目，主持。

（2） 2006.4～2008.8，“超声造影成像技术与系统”,公司合作项目，主持。

（3）  2009.1～2011.12,“聚焦超声瞬态空化机制，选择性增强与抑制及其监控成像”，国家自然科学基金青年科学基金项目，主持。

（4）  2002.9～2008.4，“256阵元相控阵高强度聚焦超声治疗系统”，公司合作项目，参与。

（5）  2003.1 -2005.12,“复合包裹靶向UCA、微血管灌注成像与间接分子成像”，国家自然科学基金面上项目，参与。

（6）  2007.1 -2010.12,“药物载体微粒(泡)、低强度聚焦超声(LIFU)精细与适形控制释放和实时监控成像”，国家自然科学基金重点项目，参与。

（7）  2006.1～2008.12，“肿瘤热消融瞬态物理和超声功能与间接分子监控成像”，教育部重大项目，参与。

（8） 2010.1-2014.12， 科技部国家重点基础研究973计划项目：易损斑块无创、高分辨超声功能与分子定量成像，参与。

（9）  2013.1-2015.12，校基金项目：聚焦超声空化多模式定量检测与实时监控成像，主持。

（10）2015.1~2018.12，“骨表微小血管脉冲逆转微泡小波变换超声造影成像及血流灌注评价”，国家自然科学基金面上项目，主持。

（11）2017.01-2019.12，校基金项目：脉冲HIFU条件下高灵敏度、高分辨、超快速次谐波空化成像，主持。

（12） 2019.01.~ 2022.12，“肺灌洗三维超声微泡灌注成像与动态传导模式评价方法及其应用”，国家自然科学基金面上项目，主持。

教材专著

教材：参编《生物医学超声学》，万明习等主编，科学出版社，2010。

专著：Chapter 7 in Wan Mingxi, Feng Yi, Gail ter Haar eds. Cavitation in Biomedicine——principle and technology，springer publisher,  2015.

发表文章

1.   钟徽，万明习，江一峰，王素品. 高强度聚焦超声软组织损伤超声监控成像与评价方法. 声学学报. 2006, 31（3）：247-254.

2.    Zhong Hui, Wan Mingxi, Jiang Yifeng, Wang Supin. Ultrasound imaging and evaluation of lesion induced by high intensity focused ultrasound (HIFU). Chinese Journal of Acoustics. 2006, 25(2): 104-115.

3.    Hui Zhong, Mingxi Wan, Yifeng Jiang, Suping Wang, Differential ultrasonic imaging for the characterization of lesions induced by high intensity focused ultrasound. Ultrasonics，2006；44, Supplement 1, 22 December 2006, Pages e285-e288. 

4.    Hui Zhong, Mingxi Wan, Yifeng Jiang, Supin Wang, Monitoring imaging of lesions induced by high intensity focused ultrasound based on differential ultrasonic attenuation and integrated backscatter estimation. Ultrasound Med Biol, 2007; 33(1): 82–94. 

5.    钟徽, 江一峰, 万明习。准实时高强度聚焦超声背向散射积分监控成像。测试技术学报。2007，21（2）：95-101。

6.   Siyuan Zhang, Mingxi Wan, Hui Zhong, Cheng Xu, Zhenzhong Liao, Huanqing Liu and Supin Wang. Dynamic Changes of Integrated Backscatter, Attenuation Coefficient and Bubble Activities due to High-Intensity Focused Ultrasound Treatment. Ultrasound in Medicine & Biology. 2009, 35(11):1828–1844.

7.   Xiaolin Gu, Hui Zhong, Mingxi Wan, et al. Parametric Perfusion Imaging Based on Low-Cost Ultrasound Flatform. Ultrasound in Med. & Biol., 2010，36（1）：130–144. 

8.   Xiaoyan Zhao, Hui Zhong, Minxi Wan, Liang Shen. Ultrasound Contrast Imaging Based on a Novel Algorithm Combined Pulse Inversion with Wavelet Transform. Ultrasound in Med. & Biol. 2011, 37(8):1292-1305.

9.   Hui Zhong, Guanhua Ding, Yanmin She，Yujin Zong，Mingxi Wan. The study of sub-harmonic cavitation imaging based on pulse inversion technique for monitoring of HIFU therapy.  Journal of Medical Imaging and Health Informatics, Volume 4, Number 3, June 2014, pp. 410-415. 

10.   Hui Zhong, Mingxi Wan. An integrated and dynamic imaging technique for simultaneously monitoring tissue damage formation and cavitation bubble activity during high intensity focused ultrasound (HIFU) therapy. Journal of Medical Imaging and Health Informatics, 2015; 5(8): 1729-1736. 

11.  Diya Wang, Hui Zhong, Yu Zhai, Hong Hu, Bowen Jing, and Mingxi Wan. The Influences of Guided Waves in Tibia on Nonlinear Scattering of Contrast Agents. Ultrasound in Medicine & Biology, 2016, 42(2):561-573. 

12.  Junbo Duan; Hui Zhong; Bowen Jing, et al. increasing axial resolution of ultrasonic imaging with a joint sparse representation model. IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control   2016; 63 (12): 2045-56.

13.  Hui Zhong, Xuejin Ma, and Mingxi Wan. differential PI-Based Subharmonic Cavitation Imaging During Pulsed High Intensity Focused Ultrasound Exposures. J. Med. Imaging Health Inf. 7(5), 922–927 (2017) 

14.  Xiaoyan Zhao, Hui Zhong*, and Mingxi Wan. Ultrasonic Imaging with Contrast Agents Combined Pulse Inversion and Generalized S-Transform. J. Med. Imaging Health Inf. 7(5), 968–981 (2017)    

15.  Taghaddos, Elaheh; Ma, Teng; Zhong, Hui; Zhou, Qifa; Wan, Mingxi; Safari, Ahmad, Fabrication and Characterization of Single-Aperture 3.5 MHz BNT-based Ultrasonic Transducer for Therapeutic Application. IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control, 2018；65(4): 582-588.

学术获奖

 

l   2016，高对比、高分辨超声微泡成像与灌注参量成像技术及系列设备，省科技进步一等奖。

l   2018，中国专利金奖。

l    2018，中国十大医学进展。