研究领域（方向）

（1）化学药物绿色合成新方法和新工艺研究；

（2）硒化学及含硒活性分子的研究； 

个人及工作简历

毛帅，男，副教授，硕士研究生导师。2009年7月获得中北大学制药工程专业工学学士学位，2012年7月、2015年7月分别获西北大学有机化学专业理学硕士学位和理学博士学位，博士论文被评选为西北大学优秀博士论文；2015年10月作为讲师入职药学院，2017年3月至2019年3月在美国密西根大学安娜堡分校（The University Of Michigan Ann Arbor）药学院从事博士后研究工作；2019年7月晋升为副教授，2020年被评选为优秀班主任。

科研项目

1.国家自然科学基金青年项目，21602169，新型亲电硒化试剂的研究，2017.01~2019.12，主持。

2.中国博士后科学基金面上资助项目，2016M592775，新型高价碘类亲电硒化试剂的研究，2016.01~2018.12，主持。

3.新教师科研支持计划，具有喹唑啉骨架的EGFR（T790M）抑制剂的研究，1191320029，2015.10~2019.07，主持。

4.中央高校基本科研业务费，1191320046，新型99mTc-膦酸类骨显像剂的设计合成及生物性质研究，2020-01~2021-12，主持。

5.企业项目，茶叶中有机硒含量检测关键技术开发，3211000066，2020.10-2021.10，主持。

学术及科研成果、专利、论文

论文发表情况：

1. Kaixiu Luo,^#Shuai Mao,^#Kun He, Xianglin Yu, Junhong Pan, Jun Lin,* ZhiHui Shao,* Yi Jin*. Highly Regioselective Synthesis of Multisubstituted Pyrroles via Ag-Catalyzed [4+1C]^insertCascade.ACS Catal.2020,10, 3733−3740.(IF：12.34)

2.Shuai Mao,Kaixiu Luo, Lu Wang, Hong-Yi Zhao, Andrea Shergalis, Minhang Xin, Nouri Neamati,* Yi Jin,* and San-Qi Zhang*, Metal-Free C-2-H Alkylation of Quinazolin-4-ones with Alkanes via Cross-Dehydrogenative Coupling.Org. Lett.2019,21, 2365–2368.(JCR一区，IF: 6.5)

3.Shuai Mao,Ya-Ru Gao, Xue-Qing Zhu, Dong-Dong Guo, and Yong-Qiang Wang*, Copper-Catalyzed Radical Reaction of N–Tosylhydrazones: Stereoselective Synthesis of (E)-Vinyl Sulfones.Org. Lett.2015,17, 1692–1695.(IF: 6.5)

4.Shuai Mao, Zhengkai Chen, Lu Wang, Daulat Bikram Khadka, Minhang Xin,Pengfei Li*, and San-Qi Zhang*，Synthesis of Aryl Trimethylstannane via BF3·OEt2-Mediated Cross-Coupling of Hexaalkyl Distannane Reagent with Aryl Triazene at Room Temperature,J. Org. Chem.2019,84, 463–471.(IF: 4.8)

5.Shuai Mao,Xue-Qing Zhu, Ya-Ru Gao, Dong-Dong Guo, Yong-Qiang Wang*,Silver-Catalyzed Two Csp3–H Coupling and One-pot Synthesis of Tetrasubstituted Furans, Thiophenes, and Pyrroles.Chem. Eur. J.2015, 11335-11339.(IF: 5.731, Hot paper)

6.Shuai Mao,Ya-Ru Gao, Shao-Liang Zhang, Dong-Dong Guo, Yong-Qiang Wang*, Copper(II)-Promoted C–C Bond Formation by Oxidative Activation of Two C(sp³)–H Bonds Adjacent to Carbonyl Group to Construct 1,4-Diketones and Tetrasubstituted Furans.Eur. J. Org. Chem.2015, 876–885.(IF: 3.154)

7.Rui-Lin Liu*,Shuai Mao, Yan Wang, Lu Wang, Yan-Hui Ge, Xin-Ya Xu, Qiang Fu. A mussel-inspired hybrid copolymer adhered to chitosan-coated micro-sized carbon fiber aerogels for highly efficient nanoparticle scavenging.Environ. Sci.: Nano,2017,4, 2164-2174.(IF:7.704)

8.Xue-Yan Yang, Ruizhe Wang, Lu Wang, Jianjun Li,Shuai Mao,*San-Qi Zhang,*Nanzheng Chen*. K₂S₂O₈-promoted C–Se bond formation to construct a-phenylseleno carbonyl compounds and a,b-unsaturated carbonyl compounds. RSC Adv., 2020,10, 28902-28905.(IF:3.119)

9. Jing-Wen Yu^#,Shuai Mao^#, Yong-Qiang Wang*,Copper-catalyzed base-accelerated direct oxidation of C–H bond to synthesize benzils, isatins, and quinoxalines with molecular oxygen as terminal oxidant.Tetrahedron Lett.2015,56, 1575–1580.(IF: 2.295)共同一作.

10.Xue‐Qing Zhu,Shuai Mao, Dong‐Dong Guo, Bin Li, Shi‐Huan Guo, Ya‐Ru Gao, Yong‐Qiang Wang, Copper-catalyzed isomerization and cyclization of E/Z-Ohaloaryl N-sulfonylhydrazones: Convenient access to 1H-indazoles.ChemCatChem2017, 9, 1084−1091.(IF:4.674)

11.Guanghui Wang, Li Liu, Hong Wang, You-Song Ding, Jing Zhou,Shuai Mao, Pengfei Li.N, B-Bidentate Boryl Ligand-Supported Iridium Catalyst for Efficient Functional-Group-Directed C–H Borylation.J. Am. Chem. Soc.2017, 139, 91.(IF:14.695)

12.Yu-Fei Wang, Ya-Ru Gao,Shuai Mao,Yan-Lei Zhang, Dong-Dong Guo, Zhao-Lei Yan, Shi-Huan Guo, and Yong-Qiang Wang*, Wacker-Type Oxidation and Dehydrogenation of Terminal Olefins Using Molecular Oxygen as the Sole Oxidant without Adding Ligand,Org. Lett.2014,16, 1610–1613.(IF: 6.5)

13.Dong Yang,Shuai Mao,Ya-Ru Gao,Dong-Dong Guo,Shi-Huan Guo,Bin Li，Yong-Qiang Wang*，Palladium-Catalyzed C-7 Alkenylation of Indolines Using Molecular Oxygen as the Sole Oxidant.RSC Adv.2015,5, 23727–23736.(IF: 3.708)

14.Zhao-Lei Yan, Wen-Liang Chen, Ya-Ru Gao,Shuai Mao, Yan-Lei Zhang and Yong-Qiang Wang*, Palladium-Catalyzed Intermolecular C2 Alkenylation of Indoles Using Oxygen as the Oxidant.Adv. Synth. Catal.2014,356, 1085–1092.(IF: 5.542)

15.Nana Li, Yan-Lei Zhang,Shuai Mao,Ya-Ru Gao, Dong-Dong Guo, and Yong-Qiang Wang*, Palladium-Catalyzed C–H Homocoupling of Furans and Thiophenes Using Oxygen as the Oxidant.Org. Lett.2014,16, 2732–2735.(IF: 6.324)

16.Yanping Liu^#, Jooyoung Chung^#, Youngjin Jang,Shuai Mao, B. Moon Kim, Yongqaing Wang, Xiaohui Guo*, Magnetically Recoverable Nanoflake-Shaped Iron Oxide /Pt Heterogeneous Catalysts and Their Excellent Catalytic Performances in Hydrogenation Reaction.ACS. Applied Mater@Interface2014,6, 1887–1892.(IF: 5.900)

17.Bo-Rui Kang, Sen Li,Shuai Mao, Yong-Xiao Cao, San-Qi Zhang*, Discovery of novel 2-benzylisoquinolin-1 (2H)-ones as potent vasodilative agents.Bioorg. Med. Chem.Lett., 2015, 25, 5808-5812.

18.Xiao-Meng Wang,Shuai Mao, Lei Cao, Xiao-Xiao Xie, Min-Hang Xin, Jia-Fang Lian,Yong-Xiao Cao, San-Qi Zhang. Modification of N-(6-(2-methoxy-3- (4-fluorophenyl sulfonamido) pyridin-5-yl)-[1,2,4] triazolo [1,5-a]pyridin-2-yl) acetamide as PI3Ksinhibitor by replacement of the acetamide group with alkylurea.Bioorg. Med. Chem.2015, 23, 5662–5671.

专利：

国际专利：Nouri Neamati and Shuai Mao, Preparation of substituted bicyclic and tetracyclic quinones and related methods of use. WO 2020181207.毛帅，张三奇，辛敏行，赵宏义，雷浩。一种非金属促进的2-烷基杂芳烃化合物的制备方法，CN 111518039 A

联系方式

电子邮箱：smao0115@xjtu.edu.cn

联系电话：15339028557

个人主页：http://gr.xjtu.edu.cn/web/smao0115

联系地址：陕西省西安市雁塔区雁塔西路76号