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白亮 教授

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  • 发布时间:2021-05-20
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白亮,博士,教授,病理学与病理生理学 博士生导师。

西北农林科技大学动物科学专业学士、动物遗传与育种专业硕士、动物学专业博士,美国西北大学Feinberg医学院病理系联合培养博士,基础医学、临床医学博士后。现为转化医学研究院心血管研究所Co-PI。

科研:研究方向为心血管疾病动物模型构建、脂代谢紊乱与动脉粥样硬化的调控机制及防治。主持国家自然科学基金、陕西省自然科学基金等项目5项。在Hepatology、Arterioscler Thromb Vasc Biol 和iScience等期刊发表SCI收录论文50余篇。

教学:为本科生、研究生、留学生主讲《医学实验动物学》、《高级医学研究英语实践》课程,参编《人类疾病动物模型》等教材2部。培养硕士研究生3名,指导大学生创新训练项目5项。

社会兼职:担任陕西省实验动物学会理事、中国实验动物学会高校专业教育和学科建设工作委员会委员。

代表性论文

1. Bai L, Li Z, Li Q, Guan H, Zhao S, Liu R, Wang R, Zhang J, Jia Y, Fan J, Wang N, Reddy JK, Shyy JY, Liu E. Mediator 1 is atherosclerosis protective by regulating macrophage polarization.Arterioscler Thromb Vasc Biol. 2017, 37(8): 1470-1481.

2. Bai L, Jia Y, Viswakarma N, Huang J, Vluggens A, Wolins NE, Jafari N, Rao MS, Borensztajn J*, Yang G*, Reddy JK*. Transcription coactivator mediator subunit MED1 is required for the development of fatty liver in the mouse. Hepatology. 2011, 53(4):1164-1174.

3. Bai L, Liu B, Ji C, Zhao S, Liu S, Wang R, Wang W, Yao P, Li X, Fu X, Yu H, Liu M, Han F, Guan N, Liu H, Liu D, Tao Y, Wang Z, Yan S, Florant G, Butcher MT, Zhang J, Zheng H, Fan J, Liu E. Hypoxic and Cold Adaptation Insights from the Himalayan Marmot Genome. iScience. 2019;11:505-507.

4. Liu B, Bai L*, Fu Y, Zhao S, Liu H, Wang R, Wang W, Li Y, Tao Y, Wang Z, Fan J, Liu E. Genetic and molecular features for hepadnavirus and plague infections in the Himalayan marmot. Genome. 2020;63(6):307-317. (通讯作者)

5. Lei L, Yang X, Su Y, Zheng H, Liu J, Liu H, Zou Y, Jiao A, Wang X, Zhang C, Zhang X, Zhang J, Zhang D, Zhou X, Shi L, Liu E, Bai L*, Sun C*, Zhang B*. Med1 controls CD8 T cell maintenance through IL-7R-mediated cell survival signalling. J Cell Mol Med. 2021;25(10):4870-4876. (通讯作者)

6. Wang Y, Bai L*, Lin Y, Chen Y, Guan H, Zhu N, Li Y, Gao S, Sun L, Zhao S, Fan J, Liu E. Combined use of probucol and cilostazol with atorvastatin attenuates atherosclerosis in moderately hypercholesterolemic rabbits. Lipids Health Dis. 2015; 29;14:82. (通讯作者)

7. Liu B, Bai L, Yu Q, Hu F, Wu J, Zhao S, Wang R, Wang W, Tao Y, Fan J, Liu E. iMarmot: an integrative platform for comparative and functional genomics of marmots. BMC Genomics. 2020;21(1):266.

8. Li Z, Martin M, Zhang J, Huang HY, Bai L, Zhang J, Kang J, He M, Li J, Maurya MR, Gupta S, Zhou G, Sangwung P, Xu YJ, Lei T, Huang HD, Jain M, Jain MK, Subramaniam S, Shyy JY. Krüppel-Like Factor 4 Regulation of Cholesterol-25-Hydroxylase and Liver X Receptor Mitigates Atherosclerosis Susceptibility. Circulation. 2017;136(14):1315-1330.

9. Wei LL, Ma N, Wu KY, Wang JX, Diao TY, Zhao SJ, Bai L, Liu E, Li ZF, Zhou W, Chen D, Li K. Protective Role of C3aR (C3a Anaphylatoxin Receptor) Against Atherosclerosis in Atherosclerosis-Prone Mice. Arterioscler Thromb Vasc Biol. 2020;40(9):2070-2083.

10. Zhang J, He Y, Yan X, Chen S, He M, Lei Y, Zhang J, Gongol B, Gu M, Miao Y, Bai L, Cui X, Wang X, Zhang Y, Fan F, Li Z, Shen Y, Chou CH, Huang HD, Malhotra A, Rabinovitch M, Jing ZC, Shyy JY. MicroRNA-483 amelioration of experimental pulmonary hypertension. EMBO Mol Med. 2020;12(5):e11303

邮箱: bailiang0922@mail.xjtu.edu.cn  

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